1KBB

Mechanistic Analyses of Catalysis in Human Pancreatic alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids

Summary for 1KBB

Entry DOI	10.2210/pdb1kbb/pdb
Descriptor	ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	amylase, glycosylation, mutagenesis, diabetes, hydrolase, glycosidase, carbohydrate metabolism, catalysis, pancreatic, enzyme, human
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	55948.80
Authors	Rydberg, E.H.,Li, C.,Maurus, R.,Overall, C.M.,Brayer, G.D.,Withers, S.G. (deposition date: 2001-11-05, release date: 2002-04-10, Last modification date: 2021-10-27)
Primary citation	Rydberg, E.H.,Li, C.,Maurus, R.,Overall, C.M.,Brayer, G.D.,Withers, S.G. Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids. Biochemistry, 41:4492-4502, 2002 Cited by PubMed: 11914097 DOI: 10.1021/bi011821z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation