1KAH

L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINE (PRODUCT), ZN AND NAD (COFACTOR)

Summary for 1KAH

Entry DOI	10.2210/pdb1kah/pdb
Related	1K75 1KAE 1KAR
Descriptor	Histidinol dehydrogenase, ZINC ION, HISTIDINE (3 entities in total)
Functional Keywords	l-histidinol dehydrogenase, homodimer, rossmann fold, 4 domains, hisd, l-histidine biosynthesis, nad cofactor, zinc, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	93405.96
Authors	Barbosa, J.A.R.G.,Sivaraman, J.,Li, Y.,Larocque, R.,Matte, A.,Schrag, J.D.,Cygler, M. (deposition date: 2001-11-02, release date: 2002-06-12, Last modification date: 2023-11-15)
Primary citation	Barbosa, J.A.R.G.,Sivaraman, J.,Li, Y.,Larocque, R.,Matte, A.,Schrag, J.D.,Cygler, M. Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc.Natl.Acad.Sci.USA, 99:1859-1864, 2002 Cited by PubMed: 11842181 DOI: 10.1073/pnas.022476199 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation