1K75

The L-histidinol dehydrogenase (hisD) structure implicates domain swapping and gene duplication.

1K75 の概要

• エントリーDOI: 10.2210/pdb1k75/pdb
• 分子名称: L-histidinol dehydrogenase, SULFATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: l-histidinol dehydrogenase, homodimer, rossmann fold, 4 domains, hisd, l-histidine biosynthesis, nad cofactor, montreal-kingston bacterial structural genomics initiative, bsgi, structural genomics, oxidoreductase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93345.39

構造登録者

Barbosa, J.A.R.G.,Sivaraman, J.,Li, Y.,Larocque, R.,Matte, A.,Schrag, J.,Cygler, M.,Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) (登録日: 2001-10-18, 公開日: 2002-02-27, 最終更新日: 2014-11-12)

• 主引用文献: Barbosa, J.A.R.G.,Sivaraman, J.,Li, Y.,Larocque, R.,Matte, A.,Schrag, J.D.,Cygler, M.; Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.; Proc.Natl.Acad.Sci.USA, 99:1859-1864, 2002; PubMed: 11842181; DOI: 10.1073/pnas.022476199

実験手法

X-RAY DIFFRACTION (1.75 Å)