1K29

Solution Structure of a DNA Duplex Containing M1G Opposite a 2 Base Pair Deletion

Summary for 1K29

• Entry DOI: 10.2210/pdb1k29/pdb
• Descriptor: 5'-D(*AP*TP*CP*GP*CP*(M1G)P*CP*GP*GP*CP*AP*TP*G)-3', 5'-D(*CP*AP*TP*GP*CP*CP*GP*CP*GP*AP*T)-3' (2 entities in total)
• Functional Keywords: two base deletion, dna adduct, malondialdehyde, dna
• Total number of polymer chains: 2
• Total formula weight: 7362.82

Authors

Schnetz-Boutaud, N.C.,Saleh, S.,Marnett, L.J.,Stone, M.P. (deposition date: 2001-09-26, release date: 2002-01-16, Last modification date: 2022-02-23)

• Primary citation: Schnetz-Boutaud, N.C.,Saleh, S.,Marnett, L.J.,Stone, M.P.; The exocyclic 1,N2-deoxyguanosine pyrimidopurinone M1G is a chemically stable DNA adduct when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene.; Biochemistry, 40:15638-15649, 2001; PubMed: 11747439; DOI: 10.1021/bi011242u

Experimental method

SOLUTION NMR