1K29

Solution Structure of a DNA Duplex Containing M1G Opposite a 2 Base Pair Deletion

1K29 の概要

• エントリーDOI: 10.2210/pdb1k29/pdb
• 分子名称: 5'-D(*AP*TP*CP*GP*CP*(M1G)P*CP*GP*GP*CP*AP*TP*G)-3', 5'-D(*CP*AP*TP*GP*CP*CP*GP*CP*GP*AP*T)-3' (2 entities in total)
• 機能のキーワード: two base deletion, dna adduct, malondialdehyde, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7362.82

構造登録者

Schnetz-Boutaud, N.C.,Saleh, S.,Marnett, L.J.,Stone, M.P. (登録日: 2001-09-26, 公開日: 2002-01-16, 最終更新日: 2024-05-22)

• 主引用文献: Schnetz-Boutaud, N.C.,Saleh, S.,Marnett, L.J.,Stone, M.P.; The exocyclic 1,N2-deoxyguanosine pyrimidopurinone M1G is a chemically stable DNA adduct when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene.; Biochemistry, 40:15638-15649, 2001; PubMed: 11747439; DOI: 10.1021/bi011242u

実験手法

SOLUTION NMR