1JYM

Crystals of Peptide Deformylase from Plasmodium falciparum with Ten Subunits per Asymmetric Unit Reveal Critical Characteristics of the Active Site for Drug Design

1JYM の概要

• エントリーDOI: 10.2210/pdb1jym/pdb
• 分子名称: Peptide Deformylase, COBALT (II) ION (3 entities in total)
• 機能のキーワード: pdf, malaria, plasmodium, deformylation, metalloenzyme, hydrolase
• 由来する生物種: Plasmodium falciparum (malaria parasite P. falciparum)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 218807.53

構造登録者

Kumar, A.,Nguyen, K.T.,Srivathsan, S.,Ornstein, B.,Turley, S.,Hirsh, I.,Pei, D.,Hol, W.G.J. (登録日: 2001-09-12, 公開日: 2002-03-13, 最終更新日: 2023-11-15)

• 主引用文献: Kumar, A.,Nguyen, K.T.,Srivathsan, S.,Ornstein, B.,Turley, S.,Hirsh, I.,Pei, D.,Hol, W.G.; Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design.; Structure, 10:357-367, 2002; PubMed: 12005434; DOI: 10.1016/S0969-2126(02)00719-0

実験手法

X-RAY DIFFRACTION (2.8 Å)