1JQ8

Design of specific inhibitors of phospholipase A2: Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Leu-Ala-Ile-Tyr-Ser at 2.0 resolution

Summary for 1JQ8

• Entry DOI: 10.2210/pdb1jq8/pdb
• Related: 1CL5 1FB2 1FE7 1FV0 1JQ9
• Descriptor: Phospholipase A2, Peptide inhibitor, SULFATE ION, ... (5 entities in total)
• Functional Keywords: neurotoxic, designed peptide, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Daboia russellii pulchella; More
• Total number of polymer chains: 3
• Total formula weight: 28101.41

Authors

Chandra, V.,Jasti, J.,Kaur, P.,Dey, S.,Betzel, C.,Singh, T.P. (deposition date: 2001-08-04, release date: 2002-11-06, Last modification date: 2023-10-25)

• Primary citation: Chandra, V.,Jasti, J.,Kaur, P.,Dey, S.,Srinivasan, A.,Betzel, C.h.,Singh, T.P.; Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).; ACTA CRYSTALLOGR.,SECT.D, 58:1813-1819, 2002; PubMed: 12351825; DOI: 10.1107/S0907444902013720

Experimental method

X-RAY DIFFRACTION (2 Å)