1JN4

The Crystal Structure of Ribonuclease A in complex with 2'-deoxyuridine 3'-pyrophosphate (P'-5') adenosine

1JN4 の概要

• エントリーDOI: 10.2210/pdb1jn4/pdb
• 関連するPDBエントリー: 1afk 1afl 1afu 1qhc
• 分子名称: Pancreatic Ribonuclease A, ADENOSINE-5'-[TRIHYDROGEN DIPHOSPHATE] P'-3'-ESTER WITH 2'-DEOXYURIDINE (3 entities in total)
• 機能のキーワード: hydrolase, ribonuclease, endonuclease, nucleotide inhibitor
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Secreted: P61823
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28054.04

構造登録者

Jardine, A.M.,Leonidas, D.D.,Jenkins, J.L.,Park, C.,Raines, R.T.,Acharya, K.R.,Shapiro, R. (登録日: 2001-07-23, 公開日: 2003-06-03, 最終更新日: 2023-08-16)

• 主引用文献: Jardine, A.M.,Leonidas, D.D.,Jenkins, J.L.,Park, C.,Raines, R.T.,Acharya, K.R.,Shapiro, R.; Cleavage of 3',5'-Pyrophosphate-Linked Dinucleotides by Ribonuclease A and Angiogenin; Biochemistry, 40:10262-10272, 2001; PubMed: 11513604; DOI: 10.1021/bi010888j

実験手法

X-RAY DIFFRACTION (1.8 Å)