1JDW

CRYSTAL STRUCTURE AND MECHANISM OF L-ARGININE: GLYCINE AMIDINOTRANSFERASE: A MITOCHONDRIAL ENZYME INVOLVED IN CREATINE BIOSYNTHESIS

1JDW の概要

• エントリーDOI: 10.2210/pdb1jdw/pdb
• 分子名称: L-ARGININE\:GLYCINE AMIDINOTRANSFERASE, BETA-MERCAPTOETHANOL (3 entities in total)
• 機能のキーワード: transferase, creatine biosynthesis, catalytic triad, reaction mechanism, novel fold, fivefold pseudosymmetry
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side (Potential): P50440
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48599.50

構造登録者

Humm, A.,Fritsche, E.,Steinbacher, S.,Huber, R. (登録日: 1997-01-22, 公開日: 1998-01-28, 最終更新日: 2011-07-13)

• 主引用文献: Humm, A.,Fritsche, E.,Steinbacher, S.,Huber, R.; Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.; EMBO J., 16:3373-3385, 1997; PubMed: 9218780; DOI: 10.1093/emboj/16.12.3373

実験手法

X-RAY DIFFRACTION (1.9 Å)