1J7V
HUMAN IL-10 / IL-10R1 COMPLEX
Summary for 1J7V
Entry DOI | 10.2210/pdb1j7v/pdb |
Descriptor | INTERLEUKIN-10, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN (3 entities in total) |
Functional Keywords | cytokine receptor complex, 4 helix bundle, class 2 receptor, interleukin-10, cytokine-receptor complex, cytokine/receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P22301 Membrane; Single-pass type I membrane protein: Q13651 |
Total number of polymer chains | 2 |
Total formula weight | 43179.00 |
Authors | Josephson, K.,Logsdon, N.,Walter, M.R. (deposition date: 2001-05-18, release date: 2001-09-19, Last modification date: 2021-10-27) |
Primary citation | Josephson, K.,Logsdon, N.J.,Walter, M.R. Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site. Immunity, 15:35-46, 2001 Cited by PubMed: 11485736DOI: 10.1016/S1074-7613(01)00169-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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