1J4I

crystal structure analysis of the FKBP12 complexed with 000308 small molecule

Summary for 1J4I

• Entry DOI: 10.2210/pdb1j4i/pdb
• Related: 1J4H
• Descriptor: FKBP12, 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID (3 entities in total)
• Functional Keywords: isomerase, rotamase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 12251.05

Authors

Li, P.,Ding, Y.,Wang, L.,Wu, B.,Shu, C.,Li, S.,Shen, B.,Rao, Z. (deposition date: 2001-09-30, release date: 2003-06-03, Last modification date: 2023-12-27)

• Primary citation: Sun, F.,Li, P.,Ding, Y.,Wang, L.,Bartlam, M.,Shu, C.,Shen, B.,Jiang, H.,Li, S.,Rao, Z.; Design and structure-based study of new potential FKBP12 inhibitors.; Biophys.J., 85:3194-3201, 2003; PubMed: 14581219; DOI: 10.1016/S0006-3495(03)74737-7

Experimental method

X-RAY DIFFRACTION (1.8 Å)