1IQ3

SOLUTION STRUCTURE OF THE EPS15 HOMOLOGY DOMAIN OF A HUMAN POB1

1IQ3 の概要

• エントリーDOI: 10.2210/pdb1iq3/pdb
• 分子名称: RALBP1-INTERACTING PROTEIN (PARTNER OF RALBP1), CALCIUM ION (2 entities in total)
• 機能のキーワード: ef-hand domain, pob1 eh domain, riken structural genomics/proteomics initiative, rsgi, structural genomics, endocytosis-exocytosis complex, endocytosis/exocytosis
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q8NFH8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12481.86

構造登録者

Koshiba, S.,Kigawa, T.,Iwahara, J.,Kikuchi, A.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2001-06-06, 公開日: 2001-06-27, 最終更新日: 2023-12-27)

主引用文献

Koshiba, S.,Kigawa, T.,Iwahara, J.,Kikuchi, A.,Yokoyama, S.
Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1).
FEBS Lett., 442:138-142, 1999

PubMed Abstract: The solution structure of the Eps15 homology (EH) domain of a human POB1 (partner of RaIBP1) has been determined by uniform 13C/15N labeling and heteronuclear multidimensional nuclear magnetic resonance spectroscopy. The POB1 EH domain consists of two EF-hand structures, and the second one binds a calcium ion. In the calcium-bound state, the orientation of the fourth alpha-helix relative to the other helices of the POB1 EH domain is slightly different from that of calbindin, and much more different from those of calmodulin and troponin C, on the basis of their atomic coordinates.

PubMed: 9928989
DOI: 10.1016/S0014-5793(98)01644-5

実験手法

SOLUTION NMR