1IPH

STRUCTURE OF CATALASE HPII FROM ESCHERICHIA COLI

1IPH の概要

• エントリーDOI: 10.2210/pdb1iph/pdb
• 分子名称: CATALASE HPII, PROTOPORPHYRIN IX CONTAINING FE (2 entities in total)
• 機能のキーワード: hydrogen peroxide, oxidoreductase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm (Probable): P21179
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 339551.76

構造登録者

Bravo, J.,Loewen, P.C.,Fita, I. (登録日: 1995-12-31, 公開日: 1997-09-04, 最終更新日: 2023-09-27)

主引用文献

Bravo, J.,Verdaguer, N.,Tormo, J.,Betzel, C.,Switala, J.,Loewen, P.C.,Fita, I.
Crystal structure of catalase HPII from Escherichia coli.
Structure, 3:491-502, 1995

PubMed Abstract: Catalase is a ubiquitous enzyme present in both the prokaryotic and eukaryotic cells of aerobic organisms. It serves, in part, to protect the cell from the toxic effects of small peroxides. Escherichia coli produces two catalases, HPI and HPII, that are quite distinct from other catalases in physical structure and catalytic properties. HPII, studied in this work, is encoded by the katE gene, and has been characterized as an oligomeric, monofunctional catalase containing one cis-heme d prosthetic group per subunit of 753 residues.

PubMed: 7663946
DOI: 10.1016/S0969-2126(01)00182-4

実験手法

X-RAY DIFFRACTION (2.8 Å)