1IPF

TROPINONE REDUCTASE-II COMPLEXED WITH NADPH AND TROPINONE

1IPF の概要

• エントリーDOI: 10.2210/pdb1ipf/pdb
• 関連するPDBエントリー: 1IPE
• 分子名称: TROPINONE REDUCTASE-II, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 8-METHYL-8-AZABICYCLO[3,2,1]OCTAN-3-ONE, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, tropane alkaloid biosynthesis, reduction of tropinone to pseudotropine, short-chain dehydrogenase, tropinone, laue diffraction, riken structural genomics/proteomics initiative, rsgi, structural genomics
• 由来する生物種: Datura stramonium (jimsonweed)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58185.73

構造登録者

Yamashita, A.,Endo, M.,Higashi, T.,Nakatsu, T.,Yamada, Y.,Oda, J.,Kato, H.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2001-05-09, 公開日: 2003-06-03, 最終更新日: 2023-10-25)

• 主引用文献: Yamashita, A.,Endo, M.,Higashi, T.,Nakatsu, T.,Yamada, Y.,Oda, J.,Kato, H.; Capturing Enzyme Structure Prior to Reaction Initiation: Tropinone Reductase-II-Substrate Complexes; BIOCHEMISTRY, 42:5566-5573, 2003; PubMed: 12741812; DOI: 10.1021/bi0272712

実験手法

X-RAY DIFFRACTION (2.5 Å)