1IOE

Human coagulation factor Xa in complex with M55532

Summary for 1IOE

• Entry DOI: 10.2210/pdb1ioe/pdb
• Descriptor: COAGULATION FACTOR XA, CALCIUM ION, (-)-7-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]TETRAHYDRO-8A-(METHOXYMETHYL)-1'-(4-PYRIDINYL)-SPIRO[5H-OXAZOLO[3,2-A]PYRAZINE-2(3H),4'-PIPERIDIN]-5-ONE, ... (4 entities in total)
• Functional Keywords: hydrolase, serine protease, blood coagulation factor, complex
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 2
• Total formula weight: 37735.15

Authors

Shiromizu, I.,Matsusue, T. (deposition date: 2001-03-08, release date: 2003-09-23, Last modification date: 2024-10-23)

• Primary citation: Matsusue, T.,Shiromizu, I.,Okamoto, A.,Nakayama, K.,Nishida, H.,Mukaihira, T.,Miyazaki, Y.,Saitou, F.,Morishita, H.,Ohnishi, S.,Mochizuki, H.; Factor Xa Specific Inhibitor That Induces the Novel Binding Model In Complex With Human FXa; To be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)