1INC

CRYSTAL STRUCTURES OF THE COMPLEX OF PORCINE PANCREATIC ELASTASE WITH TWO VALINE-DERIVED BENZOXAZINONE INHIBITORS

1INC の概要

• エントリーDOI: 10.2210/pdb1inc/pdb
• 分子名称: PORCINE PANCREATIC ELASTASE, SULFATE ION, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: hydrolase(serine proteinase)
• 由来する生物種: Sus scrofa domestica (domestic pig)
• 細胞内の位置: Secreted: P00772
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26419.00

構造登録者

Meyer, E. (登録日: 1993-03-19, 公開日: 1994-01-31, 最終更新日: 2024-10-30)

主引用文献

Radhakrishnan, R.,Presta, L.G.,Meyer Jr., E.F.,Wildonger, R.
Crystal structures of the complex of porcine pancreatic elastase with two valine-derived benzoxazinone inhibitors.
J.Mol.Biol., 198:417-424, 1987

PubMed Abstract: The crystal structures of porcine pancreatic elastase complexed to two similar benzoxazinone inhibitors are reported to 2.09 A and 1.76 A resolution, and refined to conventional R factors of 0.153 and 0.172.

PubMed: 3430613
DOI: 10.1016/0022-2836(87)90291-9

実験手法

X-RAY DIFFRACTION (1.94 Å)