1ILG
Crystal Structure of Apo Human Pregnane X Receptor Ligand Binding Domain
Summary for 1ILG
Entry DOI | 10.2210/pdb1ilg/pdb |
Related | 1ILH |
Descriptor | ORPHAN NUCLEAR RECEPTOR PXR (2 entities in total) |
Functional Keywords | nuclear receptor, multiple binding modes, xenobiotic, promiscuous, apo, gene regulation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : O75469 |
Total number of polymer chains | 1 |
Total formula weight | 36280.87 |
Authors | Watkins, R.E.,Redinbo, M.R. (deposition date: 2001-05-08, release date: 2001-06-27, Last modification date: 2023-08-16) |
Primary citation | Watkins, R.E.,Wisely, G.B.,Moore, L.B.,Collins, J.L.,Lambert, M.H.,Williams, S.P.,Willson, T.M.,Kliewer, S.A.,Redinbo, M.R. The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity. Science, 292:2329-2333, 2001 Cited by PubMed: 11408620DOI: 10.1126/science.1060762 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
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