1IHS
CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN ALPHA-THROMBIN AND NON-HYDROLYZABLE BIFUNCTIONAL INHIBITORS, HIRUTONIN-2 AND HIRUTONIN-6
Summary for 1IHS
Entry DOI | 10.2210/pdb1ihs/pdb |
Descriptor | ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUTONIN, ... (4 entities in total) |
Functional Keywords | hydrolase(serine proteinase), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P28504 |
Total number of polymer chains | 3 |
Total formula weight | 36410.39 |
Authors | Zdanov, A.,Cygler, M. (deposition date: 1993-08-04, release date: 1994-01-31, Last modification date: 2023-11-15) |
Primary citation | Zdanov, A.,Wu, S.,DiMaio, J.,Konishi, Y.,Li, Y.,Wu, X.,Edwards, B.F.,Martin, P.D.,Cygler, M. Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6. Proteins, 17:252-265, 1993 Cited by PubMed: 8272424DOI: 10.1002/prot.340170304 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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