1IG4
Solution Structure of the Methyl-CpG-Binding Domain of Human MBD1 in Complex with Methylated DNA
Summary for 1IG4
Entry DOI | 10.2210/pdb1ig4/pdb |
Descriptor | 5'-D(*GP*TP*AP*TP*CP*(5CM)P*GP*GP*AP*TP*AP*C)-3', Methyl-CpG Binding Protein (2 entities in total) |
Functional Keywords | protein-dna complex, alpha-beta, double helix, recognition via beta-sheet, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus speckle: Q9UIS9 |
Total number of polymer chains | 3 |
Total formula weight | 15869.61 |
Authors | Ohki, I.,Shimotake, N.,Fujita, N.,Jee, J.-G.,Ikegami, T.,Nakao, M.,Shirakawa, M. (deposition date: 2001-04-17, release date: 2001-05-30, Last modification date: 2024-05-22) |
Primary citation | Ohki, I.,Shimotake, N.,Fujita, N.,Jee, J.,Ikegami, T.,Nakao, M.,Shirakawa, M. Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA. Cell(Cambridge,Mass.), 105:487-497, 2001 Cited by PubMed: 11371345DOI: 10.1016/S0092-8674(01)00324-5 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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