1IES

TETRAGONAL CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN

1IES の概要

• エントリーDOI: 10.2210/pdb1ies/pdb
• 分子名称: FERRITIN, CADMIUM ION (3 entities in total)
• 機能のキーワード: apoferritin, iron storage
• 由来する生物種: Equus caballus (horse)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 119796.62

構造登録者

Granier, T.,Gallois, B.,Dautant, A.,Langlois D'Estaintot, B.,Precigoux, G. (登録日: 1996-05-28, 公開日: 1997-01-11, 最終更新日: 2024-05-22)

主引用文献

Granier, T.,Gallois, B.,Dautant, A.,Langlois d'Estaintot, B.,Precigoux, G.
Comparison of the structures of the cubic and tetragonal forms of horse-spleen apoferritin.
Acta Crystallogr.,Sect.D, 53:580-587, 1997

PubMed Abstract: Horse-spleen apoferritin is known to crystallize in three different space groups, cubic F432, tetragonal P42(1)2 and orthorhombic P2(1)2(1)2. A structure comparison of the cubic and tetragonal forms is presented here. Both crystal forms were obtained by the vapor-diffusion technique and data were collected at 2.26 A (cubic crystal) and 2.60 A (tetragonal crystal) resolution. Two main differences were observed between these crystal structures: (i) whereas intermolecular contacts only involve salt-bridge type interactions via cadmium ions in the cubic structure, two types of interactions are observed in the tetragonal crystal (cadmium-ion-mediated salt bridges and hydrogen-bonding interactions) and (ii) cadmium ions bound in the threefold axes of ferritin molecules exhibit lower site-occupation factors in the tetragonal structure than in the cubic one.

PubMed: 15299889
DOI: 10.1107/S0907444997003314

実験手法

X-RAY DIFFRACTION (2.6 Å)