1ICQ

CRYSTAL STRUCTURE OF 12-OXOPHYTODIENOATE REDUCTASE 1 FROM TOMATO COMPLEXED WITH 9R,13R-OPDA

1ICQ の概要

• エントリーDOI: 10.2210/pdb1icq/pdb
• 関連するPDBエントリー: 1ICP 1ICS
• 分子名称: 12-OXOPHYTODIENOATE REDUCTASE 1, FLAVIN MONONUCLEOTIDE, 9R,13R-12-OXOPHYTODIENOIC ACID, ... (4 entities in total)
• 機能のキーワード: beta-alpha-barrel, protein-fmn-(9r, 13r-opda)-complex, fmn-substrate-complex, oxidoreductase
• 由来する生物種: Solanum lycopersicum
• 細胞内の位置: Cytoplasm: Q9XG54
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 86383.58

構造登録者

Breithaupt, C.,Strassner, J.,Breitinger, U.,Huber, R.,Macheroux, P.,Schaller, A.,Clausen, T. (登録日: 2001-04-02, 公開日: 2001-05-16, 最終更新日: 2023-08-09)

主引用文献

Breithaupt, C.,Strassner, J.,Breitinger, U.,Huber, R.,Macheroux, P.,Schaller, A.,Clausen, T.
X-ray structure of 12-oxophytodienoate reductase 1 provides structural insight into substrate binding and specificity within the family of OYE.
Structure, 9:419-429, 2001

PubMed Abstract: 12-Oxophytodienoate reductase (OPR) is a flavin mononucleotide (FMN)-dependent oxidoreductase in plants that belongs to the family of Old Yellow Enzyme (OYE). It was initially characterized as an enzyme involved in the biosynthesis of the plant hormone jasmonic acid, where it catalyzes the reduction of the cyclic fatty acid derivative 9S,13S-12-oxophytodienoate (9S,13S-OPDA) to 1S,2S-3-oxo-2(2'[Z]-pentenyl)-cyclopentane-1-octanoate. Several isozymes of OPR are now known that show different stereoselectivities with regard to the four stereoisomers of OPDA.

PubMed: 11377202
DOI: 10.1016/S0969-2126(01)00602-5

実験手法

X-RAY DIFFRACTION (2 Å)