1ICK

LEFT-HANDED Z-DNA HEXAMER DUPLEX D(CGCGCG)2

Summary for 1ICK

• Entry DOI: 10.2210/pdb1ick/pdb
• Related: 2DCG
• Descriptor: 5'-D(*CP*GP*CP*GP*CP*G)-3', SPERMINE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: left-handed z-dna oligomer, dna
• Total number of polymer chains: 2
• Total formula weight: 3847.05

Authors

Dauter, Z.,Adamiak, D.A. (deposition date: 2001-04-01, release date: 2001-04-12, Last modification date: 2023-08-09)

Primary citation

Dauter, Z.,Adamiak, D.A.
Anomalous signal of phosphorus used for phasing DNA oligomer: importance of data redundancy.
Acta Crystallogr.,Sect.D, 57:990-995, 2001

PubMed Abstract: The crystal structure of a left-handed Z-DNA hexamer duplex d(CGCGCG)(2) has been solved based on the anomalous diffraction signal of inherent P atoms using data collected at the single wavelength of 1.54 A. The anomalous signal of about 2% of the total diffracted intensity, constant for all nucleic acids, may be generally useful for solving crystal structures of DNA and RNA oligomers. The multiplicity of intensity measurements is shown to crucially affect the data quality and the ability to solve the phase problem. The anisotropic model refined to an R factor of 8.9% at 0.95 A resolution.

PubMed: 11418767
DOI: 10.1107/S0907444901006382

Experimental method

X-RAY DIFFRACTION (0.95 Å)