1ICK

LEFT-HANDED Z-DNA HEXAMER DUPLEX D(CGCGCG)2

1ICK の概要

• エントリーDOI: 10.2210/pdb1ick/pdb
• 関連するPDBエントリー: 2DCG
• 分子名称: 5'-D(*CP*GP*CP*GP*CP*G)-3', SPERMINE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: left-handed z-dna oligomer, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 3847.05

構造登録者

Dauter, Z.,Adamiak, D.A. (登録日: 2001-04-01, 公開日: 2001-04-12, 最終更新日: 2023-08-09)

主引用文献

Dauter, Z.,Adamiak, D.A.
Anomalous signal of phosphorus used for phasing DNA oligomer: importance of data redundancy.
Acta Crystallogr.,Sect.D, 57:990-995, 2001

PubMed Abstract: The crystal structure of a left-handed Z-DNA hexamer duplex d(CGCGCG)(2) has been solved based on the anomalous diffraction signal of inherent P atoms using data collected at the single wavelength of 1.54 A. The anomalous signal of about 2% of the total diffracted intensity, constant for all nucleic acids, may be generally useful for solving crystal structures of DNA and RNA oligomers. The multiplicity of intensity measurements is shown to crucially affect the data quality and the ability to solve the phase problem. The anisotropic model refined to an R factor of 8.9% at 0.95 A resolution.

PubMed: 11418767
DOI: 10.1107/S0907444901006382

実験手法

X-RAY DIFFRACTION (0.95 Å)