1I5P

INSECTICIDAL CRYSTAL PROTEIN CRY2AA

1I5P の概要

• エントリーDOI: 10.2210/pdb1i5p/pdb
• 分子名称: PESTICIDIAL CRYSTAL PROTEIN CRY2AA (2 entities in total)
• 機能のキーワード: helical bundle, beta prism, lectin-like beta sandwich, jelly roll, toxin
• 由来する生物種: Bacillus thuringiensis serovar kurstaki
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 70907.95

構造登録者

Morse, R.J.,Stroud, R.M.,Yamamoto, T. (登録日: 2001-02-28, 公開日: 2001-05-16, 最終更新日: 2024-10-30)

主引用文献

Morse, R.J.,Yamamoto, T.,Stroud, R.M.
Structure of Cry2Aa suggests an unexpected receptor binding epitope.
Structure, 9:409-417, 2001

PubMed Abstract: Genetically modified (GM) crops that express insecticidal protein toxins are an integral part of modern agriculture. Proteins produced by Bacillus thuringiensis (Bt) during sporulation mediate the pathogenicity of Bt toward a spectrum of insect larvae whose breadth depends upon the Bt strain. These transmembrane channel-forming toxins are stored in Bt as crystalline inclusions called Cry proteins. These proteins are the active agents used in the majority of biorational pesticides and insect-resistant transgenic crops. Though Bt toxins are promising as a crop protection alternative and are ecologically friendlier than synthetic organic pesticides, resistance to Bt toxins by insects is recognized as a potential limitation to their application.

PubMed: 11377201
DOI: 10.1016/S0969-2126(01)00601-3

実験手法

X-RAY DIFFRACTION (2.2 Å)