1I32

LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS

Summary for 1I32

Related1GYP 1GYQ 1I33
DescriptorGLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, N-NAPHTHALEN-1-YLMETHYL-2'-[3,5-DIMETHOXYBENZAMIDO]-2'-DEOXY-ADENOSINE (3 entities in total)
Functional Keywordsenzyme, dehydrogenase, oxidoreductase
Biological sourceLeishmania mexicana
Cellular locationGlycosome Q27890
Total number of polymer chains6
Total molecular weight237144.6
Authors
Suresh, S.,Bressi, J.C.,Kennedy, K.J.,Verlinde, C.L.M.J.,Gelb, M.H.,Hol, W.G.J. (deposition date: 2001-02-12, release date: 2001-10-03, Last modification date: 2011-07-13)
Primary citation
Suresh, S.,Bressi, J.C.,Kennedy, K.J.,Verlinde, C.L.,Gelb, M.H.,Hol, W.G.
Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors.
J.Mol.Biol., 309:423-435, 2001
PubMed: 11371162 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2001.4588
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers130.7%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution