1I0E

CRYSTAL STRUCTURE OF CREATINE KINASE FROM HUMAN MUSCLE

1I0E の概要

• エントリーDOI: 10.2210/pdb1i0e/pdb
• 分子名称: CREATINE KINASE,M CHAIN (1 entity in total)
• 機能のキーワード: double helix, dimer, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 172680.55

構造登録者

Shen, Y.-Q.,Tang, L.,Zhou, H.-M.,Lin, Z.-J. (登録日: 2001-01-29, 公開日: 2003-04-01, 最終更新日: 2024-04-03)

主引用文献

Shen, Y.Q.,Tang, L.,Zhou, H.M.,Lin, Z.J.
Structure of human muscle creatine kinase.
Acta Crystallogr.,Sect.D, 57:1196-1200, 2001

PubMed Abstract: The crystal structure of human muscle creatine kinase has been determined by the molecular-replacement method and refined at 3.5A resolution. The structures of both the monomer and the dimer closely resemble those of the other known structures in the creatine kinase family. Two types of dimers, one with a non-crystallographic twofold symmetry axis and the other with a crystallographic twofold symmetry axis, were found to exist simultaneously in the crystal. These dimers form an infinite "double-helix"-like structure along an unusual long crystallographic 3(1) axis.

PubMed: 11517911
DOI: 10.1107/s0907444901007703

実験手法

X-RAY DIFFRACTION (3.5 Å)