1HXS

CRYSTAL STRUCTURE OF MAHONEY STRAIN OF POLIOVIRUS AT 2.2A RESOLUTION

Summary for 1HXS

• Entry DOI: 10.2210/pdb1hxs/pdb
• Descriptor: GENOME POLYPROTEIN, COAT PROTEIN VP1, GENOME POLYPROTEIN, COAT PROTEIN VP2, GENOME POLYPROTEIN, COAT PROTEIN VP3, ... (7 entities in total)
• Functional Keywords: picornavirus, poliovirus, coat protein, ab initio phase determinaion, icosahedral virus, virus
• Biological source: Human poliovirus 1; More
• Cellular location: Capsid protein VP0: Virion. Capsid protein VP4: Virion. Capsid protein VP2: Virion. Capsid protein VP3: Virion. Capsid protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion. Protease 3C: Host cytoplasm. Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P03300 P03300 P03300 P03300
• Total number of polymer chains: 4
• Total formula weight: 97707.28

Authors

Miller, S.T.,Hogle, J.M.,Filman, D.J. (deposition date: 2001-01-16, release date: 2002-01-16, Last modification date: 2023-09-20)

• Primary citation: Miller, S.T.,Hogle, J.M.,Filman, D.J.; Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution.; J.Mol.Biol., 307:499-512, 2001; PubMed: 11254378; DOI: 10.1006/jmbi.2001.4485

Experimental method

X-RAY DIFFRACTION (2.2 Å)