1HWH
1:1 COMPLEX OF HUMAN GROWTH HORMONE MUTANT G120R WITH ITS SOLUBLE BINDING PROTEIN
1HWH の概要
エントリーDOI | 10.2210/pdb1hwh/pdb |
分子名称 | GROWTH HORMONE, GROWTH HORMONE BINDING PROTEIN (2 entities in total) |
機能のキーワード | cytokine, hormone, receptor, hematopoietic, complex (hormone-receptor), complex (hormone-receptor) complex, complex (hormone/receptor) |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Secreted: P01241 Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Growth hormone-binding protein: Secreted: P10912 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 49533.78 |
構造登録者 | |
主引用文献 | Sundstrom, M.,Lundqvist, T.,Rodin, J.,Giebel, L.B.,Milligan, D.,Norstedt, G. Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution. J.Biol.Chem., 271:32197-32203, 1996 Cited by PubMed: 8943276DOI: 10.1074/jbc.271.50.32197 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.9 Å) |
構造検証レポート
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