1HUS

RIBOSOMAL PROTEIN S7

1HUS の概要

• エントリーDOI: 10.2210/pdb1hus/pdb
• 分子名称: RIBOSOMAL PROTEIN S7 (2 entities in total)
• 機能のキーワード: ribosomal protein, rna-binding protein, decoding center
• 由来する生物種: Geobacillus stearothermophilus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18230.28

構造登録者

Hosaka, H.,Nakagawa, A.,Tanaka, I. (登録日: 1997-08-08, 公開日: 1998-01-28, 最終更新日: 2024-10-16)

主引用文献

Hosaka, H.,Nakagawa, A.,Tanaka, I.,Harada, N.,Sano, K.,Kimura, M.,Yao, M.,Wakatsuki, S.
Ribosomal protein S7: a new RNA-binding motif with structural similarities to a DNA architectural factor.
Structure, 5:1199-1208, 1997

PubMed Abstract: The ribosome is a ribonucleoprotein complex which performs the crucial function of protein biosynthesis. Its role is to decode mRNAs within the cell and to synthesize the corresponding proteins. Ribosomal protein S7 is located at the head of the small (30S) subunit of the ribosome and faces into the decoding centre. S7 is one of the primary 16S rRNA-binding proteins responsible for initiating the assembly of the head of the 30S subunit. In addition, S7 has been shown to be the major protein component to cross-link with tRNA molecules bound at both the aminoacyl-tRNA (A) and peptidyl-tRNA (P) sites of the ribosome. The ribosomal protein S7 clearly plays an important role in ribosome function. It was hoped that an atomic-resolution structure of this protein would aid our understanding of ribosomal mechanisms.

PubMed: 9331423
DOI: 10.1016/S0969-2126(97)00270-0

実験手法

X-RAY DIFFRACTION (2.5 Å)