1HTL
MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
Summary for 1HTL
| Entry DOI | 10.2210/pdb1htl/pdb |
| Descriptor | HEAT-LABILE ENTEROTOXIN, SUBUNIT B, HEAT-LABILE ENTEROTOXIN, SUBUNIT A, ... (4 entities in total) |
| Functional Keywords | enterotoxin |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 7 |
| Total formula weight | 86937.35 |
| Authors | Merritt, E.A.,Hol, W.G.J. (deposition date: 1995-02-15, release date: 1995-04-20, Last modification date: 2024-10-23) |
| Primary citation | Merritt, E.A.,Sarfaty, S.,Pizza, M.,Domenighini, M.,Rappuoli, R.,Hol, W.G. Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli. Nat.Struct.Biol., 2:269-272, 1995 Cited by PubMed: 7796260DOI: 10.1038/nsb0495-269 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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