1HST

CRYSTAL STRUCTURE OF GLOBULAR DOMAIN OF HISTONE H5 AND ITS IMPLICATIONS FOR NUCLEOSOME BINDING

Summary for 1HST

Entry DOI	10.2210/pdb1hst/pdb
Descriptor	HISTONE H5 (1 entity in total)
Functional Keywords	chromosomal protein
Biological source	Gallus gallus (chicken)
Total number of polymer chains	2
Total formula weight	19578.70
Authors	Ramakrishnan, V.,Finch, J.T.,Graziano, V.,Lee, P.L.,Sweet, R.M. (deposition date: 1993-03-30, release date: 1993-10-31, Last modification date: 2024-02-07)
Primary citation	Ramakrishnan, V.,Finch, J.T.,Graziano, V.,Lee, P.L.,Sweet, R.M. Crystal structure of globular domain of histone H5 and its implications for nucleosome binding. Nature, 362:219-223, 1993 Cited by PubMed Abstract: The structure of GH5, the globular domain of the linker histone H5, has been solved to 2.5 A resolution by multiwavelength anomalous diffraction on crystals of the selenomethionyl protein. The structure shows a striking similarity to the DNA-binding domain of the catabolite gene activator protein CAP, thereby providing a possible model for the binding of GH5 to DNA. PubMed: 8384699 DOI: 10.1038/362219a0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation