1HST

CRYSTAL STRUCTURE OF GLOBULAR DOMAIN OF HISTONE H5 AND ITS IMPLICATIONS FOR NUCLEOSOME BINDING

1HST の概要

• エントリーDOI: 10.2210/pdb1hst/pdb
• 分子名称: HISTONE H5 (1 entity in total)
• 機能のキーワード: chromosomal protein
• 由来する生物種: Gallus gallus (chicken)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 19578.70

構造登録者

Ramakrishnan, V.,Finch, J.T.,Graziano, V.,Lee, P.L.,Sweet, R.M. (登録日: 1993-03-30, 公開日: 1993-10-31, 最終更新日: 2024-02-07)

主引用文献

Ramakrishnan, V.,Finch, J.T.,Graziano, V.,Lee, P.L.,Sweet, R.M.
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding.
Nature, 362:219-223, 1993

PubMed Abstract: The structure of GH5, the globular domain of the linker histone H5, has been solved to 2.5 A resolution by multiwavelength anomalous diffraction on crystals of the selenomethionyl protein. The structure shows a striking similarity to the DNA-binding domain of the catabolite gene activator protein CAP, thereby providing a possible model for the binding of GH5 to DNA.

PubMed: 8384699
DOI: 10.1038/362219a0

実験手法

X-RAY DIFFRACTION (2.6 Å)