1HP9

kappa-Hefutoxins: a novel Class of Potassium Channel Toxins from Scorpion venom

1HP9 の概要

• エントリーDOI: 10.2210/pdb1hp9/pdb
• 分子名称: kappa-hefutoxin 1 (1 entity in total)
• 機能のキーワード: scorpion toxin, gating modifier, voltage-gated potassium channel, toxin
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2664.91

構造登録者

Srinivasan, K.N.,Sivaraja, V.,Huys, I.,Sasaki, T.,Cheng, B.,Kumar, T.K.S.,Sato, K.,Tytgat, J.,Yu, C.,Brian Chia, C.S.,Ranganathan, S.,Bowie, J.H.,Kini, R.M.,Gopalakrishnakone, P. (登録日: 2000-12-12, 公開日: 2002-08-28, 最終更新日: 2022-02-23)

• 主引用文献: Srinivasan, K.N.,Sivaraja, V.,Huys, I.,Sasaki, T.,Cheng, B.,Kumar, T.K.,Sato, K.,Tytgat, J.,Yu, C.,San, B.C.,Ranganathan, S.,Bowie, H.J.,Kini, R.M.,Gopalakrishnakone, P.; kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity.; J.Biol.Chem., 277:30040-30047, 2002; PubMed: 12034709; DOI: 10.1074/jbc.M111258200

実験手法

SOLUTION NMR