1HNF

CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF THE HUMAN CELL ADHESION MOLECULE CD2 AT 2.5 ANGSTROMS RESOLUTION

Summary for 1HNF

Entry DOI	10.2210/pdb1hnf/pdb
Descriptor	CD2, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... (4 entities in total)
Functional Keywords	t lymphocyte adhesion glycoprotein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	21688.69
Authors	Bodian, D.L.,Jones, E.Y.,Harlos, K.,Stuart, D.I.,Davis, S.J. (deposition date: 1994-08-10, release date: 1995-02-07, Last modification date: 2024-10-16)
Primary citation	Bodian, D.L.,Jones, E.Y.,Harlos, K.,Stuart, D.I.,Davis, S.J. Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution. Structure, 2:755-766, 1994 Cited by PubMed Abstract: The T-lymphocyte antigen CD2 is an adhesion molecule implicated in immune responses in vivo. The extracellular regions of the human and rat homologues of CD2 share only 45% sequence identity and bind different protein ligands. Comparison of the human and rat soluble CD2 (sCD2) structures should provide insights into the structural basis of cell surface recognition. PubMed: 7994575 DOI: 10.1016/S0969-2126(94)00076-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation