1HII

COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR

1HII の概要

• エントリーDOI: 10.2210/pdb1hii/pdb
• 分子名称: HIV-2 PROTEASE, SULFATE ION, ACETYL-NH-VAL-CYCLOHEXYL-CH2[NCH2CHOH]CH2-BENZYL-VAL-NH-ACETYL, ... (4 entities in total)
• 機能のキーワード: aspartate protease, inhibited, hiv, hydrolase (aspartic proteinase)
• 由来する生物種: Human immunodeficiency virus 2
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P04584
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22222.57

構造登録者

Priestle, J.P.,Gruetter, M.G. (登録日: 1995-03-31, 公開日: 1995-07-10, 最終更新日: 2024-02-07)

• 主引用文献: Priestle, J.P.,Fassler, A.,Rosel, J.,Tintelnot-Blomley, M.,Strop, P.,Grutter, M.G.; Comparative analysis of the X-ray structures of HIV-1 and HIV-2 proteases in complex with CGP 53820, a novel pseudosymmetric inhibitor.; Structure, 3:381-389, 1995; PubMed: 7613867; DOI: 10.1016/S0969-2126(01)00169-1

実験手法