1HG9

Solution structure of DNA:RNA hybrid

Summary for 1HG9

• Entry DOI: 10.2210/pdb1hg9/pdb
• Related: 1HHW 1HHX
• Descriptor: 5- D(*CP*TP*GP*AP*TP*AP*TP*GP*C) -3, 5- R(*GP*CP*AP*UP*AP*UP*CP*AP*G) -3 (2 entities in total)
• Functional Keywords: dna-rna hybrid, dna rna hybrid, dna/rna chimeric hybrid duplex, antisense, locked nucleic acid, dna, rna, hybrid, rnase h
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 5586.58

Authors

Petersen, M.,Bondensgaard, K.,Wengel, J.,Jacobsen, J.P. (deposition date: 2000-12-13, release date: 2002-01-02, Last modification date: 2019-10-09)

• Primary citation: Bondensgaard, K.,Petersen, M.,Singh, S.K.,Rajwanshi, V.K.,Kumar, R.,Wengel, J.,Jacobsen, J.P.; Structural studies of LNA:RNA duplexes by NMR: conformations and implications for RNase H activity.; Chemistry, 6:2687-2695, 2000; PubMed: 10985717; DOI: 10.1002/1521-3765(20000804)6:15<2687::aid-chem2687>3.0.co;2-u

Experimental method

SOLUTION NMR