1HCN

STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN

1HCN の概要

• エントリーDOI: 10.2210/pdb1hcn/pdb
• 分子名称: HUMAN CHORIONIC GONADOTROPIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: hormone
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26209.16

構造登録者

Wu, H.,Lustbader, J.W.,Liu, Y.,Canfield, R.E.,Hendrickson, W.A. (登録日: 1994-07-01, 公開日: 1994-09-30, 最終更新日: 2024-11-06)

主引用文献

Wu, H.,Lustbader, J.W.,Liu, Y.,Canfield, R.E.,Hendrickson, W.A.
Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein.
Structure, 2:545-558, 1994

PubMed Abstract: Human chorionic gonadotropin (hCG) is a placental hormone that stimulates secretion of the pregnancy-sustaining steroid progesterone. It is a member of a family of glycoprotein hormones that are disulfide-rich heterodimers, with a common alpha-chain and distinctive beta-chains specific to their particular G-protein linked receptors.

PubMed: 7922031
DOI: 10.1016/S0969-2126(00)00054-X

実験手法

X-RAY DIFFRACTION (2.6 Å)