1HB5

quasi-atomic resolution model of bacteriophage PRD1 P3-shell, obtained by combined cryo-EM and X-ray crystallography.

1HB5 の概要

• エントリーDOI: 10.2210/pdb1hb5/pdb
• 関連するPDBエントリー: 1CJD 1HB7 1HB9 1HQN 1HX6
• EMDBエントリー: 1013 1014
• 分子名称: BACTERIOPHAGE PRD1 P3-SHELL (1 entity in total)
• 機能のキーワード: virus, virus/viral protein, tectiviridae, bacteriophage prd1, cryo- em, image reconstruction, icosahedral virus
• 由来する生物種: BACTERIOPHAGE PRD1
• 細胞内の位置: Virion: P22535
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 390115.97

構造登録者

San Martin, C.,Burnett, R.M.,De Haas, F.,Heinkel, R.,Rutten, T.,Fuller, S.D.,Butcher, S.J.,Bamford, D.H. (登録日: 2001-04-11, 公開日: 2001-12-05, 最終更新日: 2024-05-08)

主引用文献

Martin, C.S.,Burnett, R.M.,De Haas, F.,Heinkel, R.,Rutten, T.,Fuller, S.D.,Butcher, S.J.,Bamford, D.H.
Combined Em/X-Ray Imaging Yields a Quasi-Atomic Model of the Adenovirus-Related Bacteriophage Prd1 and Shows Key Capsid and Membrane Interactions.
Structure, 9:917-, 2001

PubMed Abstract: The dsDNA bacteriophage PRD1 has a membrane inside its icosahedral capsid. While its large size (66 MDa) hinders the study of the complete virion at atomic resolution, a 1.65-A crystallographic structure of its major coat protein, P3, is available. Cryo-electron microscopy (cryo-EM) and three-dimensional reconstruction have shown the capsid at 20-28 A resolution. Striking architectural similarities between PRD1 and the mammalian adenovirus indicate a common ancestor.

PubMed: 11591347
DOI: 10.1016/S0969-2126(01)00642-6

実験手法

ELECTRON MICROSCOPY (12 Å)