1HAV

HEPATITIS A VIRUS 3C PROTEINASE

1HAV の概要

• エントリーDOI: 10.2210/pdb1hav/pdb
• 分子名称: HEPATITIS A VIRUS 3C PROTEINASE, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: polyprotein, coat protein, core protein, rna-directed rna polymerase, hydrolase, thiol protease
• 由来する生物種: Hepatitis A virus; 詳細
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein VP1-2A: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3ABC: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3AB: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P08617 P08617
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47892.58

構造登録者

Bergmann, E.M.,James, M.N.G. (登録日: 1996-10-23, 公開日: 1996-12-23, 最終更新日: 2024-04-03)

• 主引用文献: Bergmann, E.M.,Mosimann, S.C.,Chernaia, M.M.,Malcolm, B.A.,James, M.N.; The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition.; J.Virol., 71:2436-2448, 1997; PubMed: 9032381

実験手法

X-RAY DIFFRACTION (2 Å)