1H8Y

Crystal structure of the class D beta-lactamase OXA-13 in complex with meropenem

Summary for 1H8Y

• Entry DOI: 10.2210/pdb1h8y/pdb
• Related: 1H8Z
• Descriptor: BETA-LACTAMASE, (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, SULFATE ION, ... (4 entities in total)
• Functional Keywords: hydrolase, beta-lactamase, class d, oxa-13, meropenem, acyl- enzyme
• Biological source: PSEUDOMONAS AERUGINOSA
• Total number of polymer chains: 2
• Total formula weight: 56055.73

Authors

Pernot, L.,Frenois, F.,Rybkine, T.,L'Hermite, G.,Petrella, S.,Delettre, J.,Jarlier, V.,Collatz, E.,Sougakoff, W. (deposition date: 2001-02-17, release date: 2001-07-12, Last modification date: 2013-02-06)

• Primary citation: Pernot, L.,Frenois, F.,Rybkine, T.,L'Hermite, G.,Petrella, S.,Delettre, J.,Jarlier, V.,Collatz, E.,Sougakoff, W.; Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem; J.Mol.Biol., 310:859-, 2001; PubMed: 11453693; DOI: 10.1006/JMBI.2001.4805

Experimental method

X-RAY DIFFRACTION (2 Å)