1H3H

Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain

1H3H の概要

• エントリーDOI: 10.2210/pdb1h3h/pdb
• 分子名称: GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2 (2 entities in total)
• 機能のキーワード: protein-binding, complex (sh3-peptide), t-cell signaling, sh3 domain, sh2 domain, protein binding
• 由来する生物種: MUS MUSCULUS (HOUSE MOUSE); 詳細
• 細胞内の位置: Nucleus (By similarity): O89100
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8093.09

構造登録者

Liu, Q.,Berry, D.,Nash, P.,Pawson, T.,McGlade, C.J.,Li, S.S. (登録日: 2002-09-03, 公開日: 2003-03-06, 最終更新日: 2024-05-15)

• 主引用文献: Liu, Q.,Berry, D.,Nash, P.,Pawson, T.,Mcglade, C.J.,Li, S.S.; Structural Basis for Specific Binding of the Gads SH3 Domain to an Rxxk Motif-Containing Slp-76 Peptide: A Novel Mode of Peptide Recognition; Mol.Cell, 11:471-, 2003; PubMed: 12620234; DOI: 10.1016/S1097-2765(03)00046-7

実験手法

SOLUTION NMR