1H10

HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE

Summary for 1H10

Entry DOI	10.2210/pdb1h10/pdb
Descriptor	RAC-ALPHA SERINE/THREONINE KINASE, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE (3 entities in total)
Functional Keywords	transferase, signalling protein, phosphoinositides, protein kinase b, pleckstrin, inositol tetrakisphophate, phosphorylation, serine/threonine protein kinase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	15440.47
Authors	Thomas, C.C.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. (deposition date: 2002-07-01, release date: 2003-06-27, Last modification date: 2019-05-22)
Primary citation	Thomas, C.C.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate Curr.Biol., 12:1256-, 2002 Cited by PubMed: 12176338 DOI: 10.1016/S0960-9822(02)00972-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation