1H10

HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE

1H10 の概要

• エントリーDOI: 10.2210/pdb1h10/pdb
• 分子名称: RAC-ALPHA SERINE/THREONINE KINASE, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE (3 entities in total)
• 機能のキーワード: transferase, signalling protein, phosphoinositides, protein kinase b, pleckstrin, inositol tetrakisphophate, phosphorylation, serine/threonine protein kinase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15440.47

構造登録者

Thomas, C.C.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. (登録日: 2002-07-01, 公開日: 2003-06-27, 最終更新日: 2019-05-22)

• 主引用文献: Thomas, C.C.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F.; High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate; Curr.Biol., 12:1256-, 2002; PubMed: 12176338; DOI: 10.1016/S0960-9822(02)00972-7

実験手法

X-RAY DIFFRACTION (1.4 Å)