1H0Q

NMR solution structure of a fully modified locked nucleic acid (LNA) hybridized to RNA

Summary for 1H0Q

• Entry DOI: 10.2210/pdb1h0q/pdb
• Descriptor: 5-D(*(LKC)P*(TLN)P*(LCG)P*(LCA)P*(TLN)P*(LCA)P* (TLN)P*(LCG)P*(LCC))-3, 5-R(*GP*CP*AP*UP*AP*UP*CP*AP*G)-3 (2 entities in total)
• Functional Keywords: dna-rna hybrid, lna, rna, locked nucleic acid, hybrid, dna/rna hybrid
• Total number of polymer chains: 2
• Total formula weight: 5786.74

Authors

Rasmussen, J.,Petersen, M.,Nielsen, K.E.,Kumar, R.,Wengel, J.,Jacobsen, J.P. (deposition date: 2002-06-27, release date: 2003-07-17, Last modification date: 2011-07-13)

• Primary citation: Nielsen, K.E.,Rasmussen, J.,Kumar, R.,Wengel, J.,Jacobsen, J.P.,Petersen, M.; NMR Studies of Fully Modified Locked Nucleic Acid (Lna) Hybrids: Solution Structure of an Lna:RNA Hybrid and Characterization of an Lna:RNA Hybrid; Bioconjug.Chem., 15:449-, 2004; PubMed: 15149171; DOI: 10.1021/BC034145H

Experimental method

SOLUTION NMR