1GYQ

CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE FROM LEISHMANIA MEXICANA IN COMPLEX WITH N6-BENZYL-NAD

1GYQ の概要

• エントリーDOI: 10.2210/pdb1gyq/pdb
• 分子名称: PROTEIN (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), N6-BENZYL-NICOTINAMIDE-ADENINE-DINUCLEOTIDE (2 entities in total)
• 機能のキーワード: oxidoreductase (aldehyde(d)-nad+(a)), oxidoreductase
• 由来する生物種: Leishmania mexicana
• 細胞内の位置: Glycosome: Q27890
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 157786.71

構造登録者

Suresh, S.,Hol, W. (登録日: 1999-03-05, 公開日: 1999-03-16, 最終更新日: 2023-08-09)

• 主引用文献: Aronov, A.M.,Suresh, S.,Buckner, F.S.,Van Voorhis, W.C.,Verlinde, C.L.,Opperdoes, F.R.,Hol, W.G.,Gelb, M.H.; Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.; Proc.Natl.Acad.Sci.USA, 96:4273-4278, 1999; PubMed: 10200252; DOI: 10.1073/pnas.96.8.4273

実験手法

X-RAY DIFFRACTION (3.4 Å)