1GYP

CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM LEISHMANIA MEXICANA: IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN AND A NEW POSITION FOR THE INORGANIC PHOSPHATE BINDING SITE

1GYP の概要

• エントリーDOI: 10.2210/pdb1gyp/pdb
• 分子名称: GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, PHOSPHATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: oxidoreductase (aldehyde(d)-nad+(a))
• 由来する生物種: Leishmania mexicana
• 細胞内の位置: Glycosome: Q27890
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 158185.98

構造登録者

Kim, H.,Feil, I.K.,Verlinde, C.L.M.J.,Petra, P.H.,Hol, W.G.J. (登録日: 1995-08-01, 公開日: 1995-12-07, 最終更新日: 2024-02-07)

• 主引用文献: Kim, H.,Feil, I.K.,Verlinde, C.L.,Petra, P.H.,Hol, W.G.; Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site.; Biochemistry, 34:14975-14986, 1995; PubMed: 7578111; DOI: 10.1021/bi00046a004

実験手法

X-RAY DIFFRACTION (2.8 Å)