1GXC
FHA domain from human Chk2 kinase in complex with a synthetic phosphopeptide
Summary for 1GXC
Entry DOI | 10.2210/pdb1gxc/pdb |
Descriptor | SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE (3 entities in total) |
Functional Keywords | phosphoprotein-binding domain, checkpoint kinase, transferase, serine/threonine-protein kinase |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Isoform 2: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 9: Nucleus. Isoform 12: Nucleus. Nucleus, PML body: O96017 |
Total number of polymer chains | 8 |
Total formula weight | 75587.18 |
Authors | Li, J.,Williams, B.L.,Haire, L.F.,Goldberg, M.,Wilker, E.,Durocher, D.,Yaffe, M.B.,Jackson, S.P.,Smerdon, S.J. (deposition date: 2002-04-02, release date: 2002-06-13, Last modification date: 2016-12-21) |
Primary citation | Li, J.,Williams, B.L.,Haire, L.F.,Goldberg, M.,Wilker, E.,Durocher, D.,Yaffe, M.B.,Jackson, S.P.,Smerdon, S.J. Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2 Mol.Cell, 9:1045-, 2002 Cited by PubMed: 12049740DOI: 10.1016/S1097-2765(02)00527-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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