1GWI

The 1.92 A structure of Streptomyces coelicolor A3(2) CYP154C1: A new monooxygenase that functionalizes macrolide ring systems

Summary for 1GWI

• Entry DOI: 10.2210/pdb1gwi/pdb
• Descriptor: CYTOCHROME P450 154C1, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
• Functional Keywords: oxidoreductase, streptomyces, cyp154c1, macrolide antibiotics, 12- and 14- carbon macrolactone monooxygenase, heme, oxidoreductase.
• Biological source: STREPTOMYCES COELICOLOR
• Total number of polymer chains: 2
• Total formula weight: 90960.65

Authors

Podust, L.M.,Kim, Y.,Arase, M.,Neely, B.A.,Beck, B.J.,Bach, H.,Sherman, D.H.,Lamb, D.C.,Kelly, S.L.,Waterman, M.R. (deposition date: 2002-03-15, release date: 2003-01-29, Last modification date: 2019-05-08)

• Primary citation: Podust, L.M.,Kim, Y.,Arase, M.,Neely, B.A.,Beck, B.J.,Bach, H.,Sherman, D.H.,Lamb, D.C.,Kelly, S.L.,Waterman, M.R.; The 1.92 A Structure of Streptomyces Coelicolor A3(2) Cyp154C1: A New Monooxygenase that Functionalizes Macrolide Ring Systems; J.Biol.Chem., 278:12214-, 2003; PubMed: 12519772; DOI: 10.1074/JBC.M212210200

Experimental method

X-RAY DIFFRACTION (1.92 Å)