1GUM
HUMAN GLUTATHIONE TRANSFERASE A4-4 WITHOUT LIGANDS
Summary for 1GUM
Entry DOI | 10.2210/pdb1gum/pdb |
Descriptor | PROTEIN (GLUTATHIONE TRANSFERASE A4-4) (2 entities in total) |
Functional Keywords | glutathione transferase, oxidative stress, alkenal degradation, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O15217 |
Total number of polymer chains | 8 |
Total formula weight | 205904.75 |
Authors | Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. (deposition date: 1998-06-11, release date: 1999-01-27, Last modification date: 2023-08-09) |
Primary citation | Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products J.Mol.Biol., 288:427-439, 1999 Cited by PubMed: 10329152DOI: 10.1006/jmbi.1999.2697 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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