1GO9

Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.

1GO9 の概要

• エントリーDOI: 10.2210/pdb1go9/pdb
• 分子名称: CORTICOTROPIN RELEASING HORMONE (1 entity in total)
• 機能のキーワード: hormone, corticotropin releasing hormone, synthetic analogues, solid phase synthesis, solutions structure
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Secreted : P06850
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4734.44

構造登録者

Spyroulias, G.A.,Papazacharias, S.,Pairas, G.,Cordopatis, P. (登録日: 2001-10-20, 公開日: 2001-10-31, 最終更新日: 2016-12-21)

• 主引用文献: Spyroulias, G.A.,Papazacharias, S.,Pairas, G.,Cordopatis, P.; Monitoring the Structural Consequences of Phe12-->D-Phe and Leu15-->Aib Substitution in Human/Rat Corticotropin Releasing Hormone. Implications for Design of Crh Antagonists.; Eur.J.Biochem., 269:6009-, 2002; PubMed: 12473096; DOI: 10.1046/J.1432-1033.2002.03278.X

実験手法

SOLUTION NMR